Publications

Meier-Abt, Fabienne; Kraemer, Dennis; Braun, Nils; Reinehr, Michael; Stutz-Grunder, Eveline; Steindl, Katharina; Rauch, Anita (2024).
Further evidence that the neurodevelopmental gene FBXW7 predisposes to Wilms tumor.  PMID: 38169111DOI: 10.1002/ajmg.a.63528American Journal of Medical Genetics Part A. 2024 Jan 02. Epub ahead of print.

Marija Buljan , Amir Banaei-Esfahani , Peter Blattmann, Fabienne Meier-Abt, Wenguang Shao,  lga Vitek, Hua Tang, Ruedi Aebersold (2023). A computational framework for the inference of protein complex remodeling from whole-proteome measurements. 
PMID: 37749212, DOI: 10.1038/s41592-023-02011-w, Nat Methods. 2023 Sep 25. Online ahead of print.

Tan G, Wolski WE, Kummer S, Hofstetter M, Theocharides APA, Manz MG, Aebersold R, Meier-Abt F. Proteomic identification of proliferation and progression markers in human polycythemia vera stem and progenitor cells. Blood Adv. 2022 Jun 14;6(11):3480-3493.

Mende N*, Bastos HP*, Santoro A, Mahbubani KT, Ciaurro V, Calderbank EF, Quiroga Londoño M, Sham K, Mantica G, Morishima T, Mitchell E, Lidonnici MR, Meier-Abt F, Hayler D, Jardine L, Curd A, Haniffa M, Ferrari G, Takizawa H, Wilson NK, Göttgens B, Saeb-Parsy K, Frontini M, Laurenti E. Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans. Blood. 2022 Jun 9;139(23):3387-3401.

Meier-Abt F*, Lu J*, Cannizzaro E, Pohly MF, Kummer S, Pfammatter S, Kunz L, Collins BC, Nadeu F, Lee KS, Xue P, Gwerder M, Roiss M, Hüllein J, Scheinost S, Dietrich S, Campo E, Huber W, Aebersold R, Zenz T. The protein landscape of chronic lymphocytic leukemia. Blood. 2021 Dec 16;138(24):2514-2525.

Lu J*, Cannizzaro E*, Meier-Abt F, Scheinost S, Bruch PM, Giles HA, Lütge A, Hüllein J, Wagner L, Giacopelli B, Nadeu F, Delgado J, Campo E, Mangolini M, Ringshausen I, Böttcher M, Mougiakakos D, Jacobs A, Bodenmiller B, Dietrich S, Oakes CC, Zenz T, Huber W. Multi-omics reveals clinically relevant proliferative drive associated with mTOR-MYC-OXPHOS activity in chronic lymphocytic leukemia. Nat Cancer. 2021 Aug;2(8):853-864.

Tan G, Meier-Abt F. Differential expression of hydroxyurea transporters in normal and polycythemia vera hematopoietic stem and progenitor cell subpopulations. Exp Hematol. 2021 May;97:47-56.

Meier-Abt F, Wolski WE, Tan G, Kummer S, Amon S, Manz MG*, Aebersold R*, Theocharides APA*. Reduced CXCL4/PF4 expression as a driver of increased human hematopoietic stem and progenitor cell proliferation in polycythemia vera. Blood Cancer J. 2021 Feb 11;11(2):31.

Amon S*, Meier-Abt F*, Gillet LC, Dimitrieva S, Theocharides APA, Manz MG, Aebersold R. Sensitive quantitative proteomics of human hematopoietic stem and progenitor cells by data-independent acquisition mass spectrometry. Mol Cell Proteomics. 2019 Jul;18(7):1454-1467.

Muenst S*, Mechera R*, Däster S, Piscuoglio S, Ng CKY, Meier-Abt F, Weber WP*, Soysal SD*. Pregnancy at early age is associated with a reduction of progesterone-responsive cells and epithelial Wnt signaling in human breast tissue. Oncotarget. 2017 Apr 4;8(14):22353-22360.

Clarke C, Dontu G, Hilton H, Meier-Abt F, Sartorius C. Preface: special issue on the hormonal regulation of stem and progenitor cells in the breast. J Mammary Gland Biol Neoplasia. 2015 Jun;20(1-2):5-7. Guest Editorial.

Meier-Abt F, Bentires-Alj M, Rochlitz C. Breast cancer prevention: lessons to be learned from mechanisms of early pregnancy-mediated breast cancer protection. Cancer Res. 2015 Mar 1;75(5):803-7. Perspective.

Meier-Abt F, Brinkhaus H, Bentires-Alj M. Early but not late pregnancy induces lifelong reductions in the proportion of mammary progesterone sensing cells and epithelial Wnt signaling. Breast Cancer Res. 2014;16(2):402.

Meier-Abt F, Bentires-Alj M. How pregnancy at early age protects against breast cancer. Trends Mol Med. 2014 Mar;20(3):143-53. Review.

Meier-Abt F, Milani E, Roloff T, Brinkhaus H, Duss S, Meyer DS, Klebba I, Balwierz PJ, van Nimwegen E, Bentires-Alj M. Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium. Breast Cancer Res. 2013 Apr 29;15(2):R36.

Meier-Abt F, Strasser B. Balancing safety and availability: a historical perspective on the pace of drug approval. Yale J Biol Med. 2009;82(4):181-229.

Meier-Abt F*, Hammann-Hänni A*, Stieger B, Ballatori N, Boyer JL. The organic anion transport polypeptide 1d1 (Oatp1d1) mediates hepatocellular uptake of phalloidin and microcystin into skate liver. Toxicol Appl Pharmacol. 2007 Feb 1;218(3):274-9.

Meier-Abt F, Mokrab Y, Mizuguchi K. Organic anion transporting polypeptides of the OATP/SLCO superfamily: identification of new members in nonmammalian species, comparative modeling and a potential transport mode. J Membr Biol. 2005 Dec;208(3):213-27.

Meier-Abt F, Hagenbuch B, Ballatori N, Boyer JL. Phalloidin uptake systems in elasmobranch liver. MDIBL Bulletin. 2005;44:88-90.

Meier-Abt F, Faulstich H, Hagenbuch B. Identification of phalloidin uptake systems of rat and human liver. Biochim Biophys Acta. 2004 Jul 1;1664(1):64-9.

Hagenbuch B, Ismair MG, Fischer W, Meier-Abt F, Kullak-Ublick GA, Meier PJ. Identification of specific substrates for some multispecific organic anion transporting polypeptides. Novo Acta Leopoldina. 2003;87:199-204. Book chapter.

* these authors contributed equally